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谢奇强，男，1993年6月出生。2025年4月以弘深青年学者（A岗）加入重庆大学化学化工学院，任硕士/博士生导师。2014年本科毕业于上海大学，随后保送至中科院上海有机化学研究所攻读博士学位（导师：胡金波研究员），并于2019年6月获理学博士学位。读博期间从事有机氟化学研究，聚焦二氟卡宾可控插入反应。2019年7月-2020年1月留组担任研究助理。2020年2月-2025年1月在美国芝加哥大学进行博士后研究（合作导师：Guangbin Dong教授），从事有机硼化学研究，聚焦Matteson反应的拓展与应用。主持重庆大学科研启动基金。迄今为止在Nat. Synth.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Acc. Chem. Res.等国际知名期刊发表论文20余篇。 |
联系方式
电话：18801912740
e-mail: qqxie@cqu.edu.cn
研究方向
主族元素化学，包括有机膦化学、有机氟化学
代表性论文、专著和专利
1. Qiqiang Xie；Thomas H. Tugwell, Mithun C. Madhusudhanan, Jiahao Li, Peng Liu*, and Guangbin Dong*. Enantioconvergent Carbenoid Insertion into Carbon−Boron Bonds. Nat. Synth. 2025, accepted.
2. Qiqiang Xie; Jinbo Hu*. A Journey of the Development of Privileged Difluorocarbene Reagents TMSCF2X (X = Br, F, Cl) for Organic Synthesis, Acc. Chem. Res., 2024, 57, 693.
3. Qiqiang Xie; Rui Zhang; Guangbin Dong*. Programmable Amine Synthesis via Iterative Boron Homologation, Angew. Chem. Int. Ed., 2023, 62, e202307118.
4. Qiqiang Xie and Guangbin Dong*. Programmable Ether Synthesis Enabled by Oxa-Matteson Reaction. J. Am. Chem. Soc. 2022, 144, 8498.
5. Qiqiang Xie and Guangbin Dong*. Aza-Matteson Reactions via Controlled Mono- and Double-Methylene Insertions into Nitrogen–Boron Bonds. J. Am. Chem. Soc. 2021, 143, 14422.
6. Qiqiang Xie, Ziyue Zhu, Lingchun Li, Chuanfa Ni, and Jinbo Hu*. A General Protocol for C-H Difluoromethylation of Carbon Acids with TMSCF2Br. Angew. Chem. Int. Ed. 2019, 58, 6405.
7. Qiqiang Xie, Lingchun Li, Ziyue Zhu, Rongyi Zhang, Chuanfa Ni, and Jinbo Hu*. From C1 to C2: TMSCF3 as a Precursor for Pentafluoroethylation. Angew. Chem. Int. Ed. 2018, 57, 13211.
8. Qiqiang Xie, Chuanfa Ni*, Rongyi Zhang, Lingchun Li, Jian Rong, and Jinbo Hu*. Efficient Difluoromethylation of Alcohols Using TMSCF2Br as a Unique and Practical Difluorocarbene Reagent under Mild Conditions. Angew. Chem. Int. Ed. 2017, 56, 3206.
9. Qiqiang Xie, Ziyue Zhu, Lingchun Li, Chuanfa Ni, and Jinbo Hu*. Controllable double CF2-insertion into sp2 C–Cu bond using TMSCF3: a facile access to tetrafluoroethylene-bridged structures. Chem. Sci. 2020, 11, 276.
10. Qiqiang Xie and Jinbo Hu*. Chen's Reagent: A Versatile Reagent for Trifluoromethylation, Difluoromethylenation, and Difluoroalkylation in Organic Synthesis. Chin. J. Chem. 2020, 38, 202.
11. Qiqiang Xie, Ziyue Zhu, Chuanfa Ni, and Jinbo Hu*. Nucleophilic (Phenylsulfonyl/arylthio)difluoromethylation of Aldehydes with TMSCF2Br: A Three-Component Strategy. Org. Lett. 2019, 21, 9138.
12. Shitao Pan, Qiqiang Xie (co-first author), Xiu Wang, Qian Wang, Chuanfa Ni, and Jinbo Hu*. Copper-mediated pentafluoroethylation of organoboronates and terminal alkynes with TMSCF3. Chem. Commun. 2022, 58, 5156.
13. Shitao Pan, Qiqiang Xie, Xiu Wang, Rumin Huang, Taige Kong, Chuanfa Ni, and Jinbo Hu*. Controllable Double Difluoromethylene Insertions into S−Cu Bonds: (Arylthio)tetrafluoroethylation of Aryl Iodides with TMSCF2Br. Angew. Chem. Int. Ed. 2024, 63, e202400839.
14. An Liu, Chuanfa Ni, Qiqiang Xie, and Jinbo Hu*. Transition-Metal-Free Controllable Single and Double Difluoromethylene Formal Insertions into C−H Bonds of Aldehydes with TMSCF2Br. Angew. Chem. Int. Ed. 2023, 62, e202217088.
15. An Liu, Shuo Sun, Qiqiang Xie, Rumin Huang, Taige Kong, Chuanfa Ni, and Jinbo Hu*. From intramolecular cyclization to intermolecular hydrolysis: TMSCF2Br-enabled carbonylation of aldehydes/ketones and amines to α-hydroxyamides. Org. Chem. Front. 2023, 10, 5343.
16. An Liu, Chuanfa Ni, Qiqiang Xie, and Jinbo Hu*. TMSCF2Br-Enabled Fluorination–Aminocarbonylation of Aldehydes: Modular Access to α-Fluoroamides. Angew. Chem. Int. Ed. 2022, 61, e202115467.
17. Rongyi Zhang, Qigang Li, Qiqiang Xie, Chuanfa Ni, and Jinbo Hu*. Difluorocarbene-Induced Ring-Opening Difluoromethylation-Halogenation of Cyclic (Thio)Ethers with TMSCF2X (X=Br, Cl). Chem. Eur. J. 2021, 27, 17773.
18. Cuiwen Kuang, Xin Zhou, Qiqiang Xie, Chuanfa Ni, Yucheng Gu, and Jinbo Hu*. Generation of Carbocations under Photoredox Catalysis: Electrophilic Aromatic Substitution with 1-Fluoroalkylbenzyl Bromides. Org. Lett. 2020, 22, 8670.
19. Rongyi Zhang, Chuanfa Ni, Qiqiang Xie, and Jinbo Hu*. Difluoromethylation of alcohols with TMSCF2Br in water: A new insight into the generation and reactions of difluorocarbene in a two-phase system. Tetrahedron 2020, 76, 131676.
20. Qian Wang, Chuanfa Ni, Mingyou Hu, Qiqiang Xie, Qinghe Liu, Shitao Pan, and Jinbo Hu*. From C1 to C3: Copper-Catalyzed gem-Bis(trifluoromethyl)olefination of α-Diazo Esters with TMSCF3. Angew. Chem. Int. Ed. 2020, 59, 8507.
21. Lingchun Li, Chuanfa Ni, Qiqiang Xie, Mingyou Hu, Fei Wang, and Jinbo Hu*. TMSCF3 as a Convenient Source of CF2=CF2 for Pentafluoroethylation, (Aryloxy)tetrafluoroethylation, and Tetrafluoroethylation. Angew. Chem. Int. Ed. 2017, 56, 9971.
22. Mingyou Hu, Qiqiang Xie, Xinjin Li, Chuanfa Ni, and Jinbo Hu*. Copper-Mediated Deuterotrifluoromethylation of α-Diazo Esters. Chin. J. Chem. 2016, 34, 469.
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