Contact information

Research direction

Synthetic organic chemistry and bioinorganic chemistry

Representative papers, monographs and patents

[15] Haoyin Yuan; Wenhao Yin; Jili Hu; Yang Li* “3-Sulfonyloxyaryl(mesityl)iodonium Triflates as 1,2-Benzdiyne Precursors with Activation via ortho-Deprotonative Elimination Strategy” Nat. Comm. 2023, accepted.

[14] Zhonghong Chen; Min Tan; Chunhui Shan; Xiaoling Yuan; Liyuan Chen; Jiarong Shi; Yu Lan; Yang Li* “Aryne 1,4-Disubstitution and Remote Diastereoselective 1,2,4-Trisubstitution via a Nucleophilic Annulation−[5,5]-Sigmatropic Rearrangement Process” Angew. Chem., Int. Ed. 2022, e202212160.

[13] Lianggui Li; Chunhui Shan; Jiarong Shi; Wensheng Li; Yu Lan;* Yang Li* “The Stannum–Ene Reactions of Benzyne and Cyclohexyne with Superb Chemoselectivity for Cyclohexyne” Angew. Chem., Int. Ed. 2022, e202117351.

[12] Jiarong Shi; Lianggui Li; Chunhui Shan; Zhonghong Chen; Liang Dai; Min Tan; Yu Lan;* Yang Li* “Benzyne 1,2,4-Trisubstitution and Dearomative 1,2,4-Trifunctionalization” J. Am. Chem. Soc. 2021, 143, 10530-10536.

[11] Yang Li* “New Strategies in recent Aryne Chemistry” in “Modern Aryne Chemistry”. Chapter 8, Editor: A. T. Biju, Wiley-VCH, 2020, ISBN: 978-3-527-82308-6.

[10] Jiarong Shi; Liangui Li; Yang Li* “o-Silylaryl Triflates: A Journey of Kobayashi Aryne Precursors” Chem. Rev. 2021, 121, 3892-4044.

[9] Jiarong Shi; Lianggui Li; Chunhui Shan; Junli Wang; Zhonghong Chen; Rongrong Gu; Jia He; Min Tan; Yu Lan;* Yang Li* “Aryne 1,2,3,5-Tetrasubstitution Enabled by 3‑Silylaryne and Allyl Sulfoxide via an Aromatic 1,3-Silyl Migration” J. Am. Chem. Soc. 2021, 143, 2178-2184.

[8] Jia He; Dachuan Qiu; Yang Li* “Strategies toward Aryne Multifunctionalization via 1,2-Benzdiyne and Benzyne” Acc. Chem. Res. 2020, 53, 508-519.

[7] Jia He; Zizi Jia; Hongcheng Tan; Xiaohua Luo; Dachuan Qiu; Jiarong Shi; Hai Xu; Yang Li* “Arene Trifunctionalization with Highly Fused Ring Systems through a Domino Aryne Nucleophilic and Diels-Alder Cascade” Angew. Chem., Int. Ed. 2019, 58, 18513-18518.

[6] Dachuan Qiu; Jiarong Shi; Qianyu Guo; Qiuxia Xu; Baosheng Li; Yang Li* “Cyclohexenynone Precursors: Preparation via Oxidative Dearomatization Strategy and Reactivity” J. Am. Chem. Soc. 2018, 140, 13214-13218.

[5] Hai Xu; Jia He; Jiarong Shi; Liang Tan; Dachuan Qiu; Xiaohua Luo; Yang Li* “Domino Aryne Annulation via Nucleophilic-Ene Process” J. Am. Chem. Soc. 2018, 140, 3555-3559. (supplementary cover article)

[4] Jiarong Shi; Yuanyuan Li; Yang Li* “Aryne Multifunctionalization with Benzdiyne and Benztriyne Equivalents” Chem. Soc. Rev. 2017, 46, 1707-1719.

[3] Jiarong Shi; Hai Xu; Dachuan Qiu; Jia He; Yang Li* “Selective Aryne Formation via Grob Fragmentation from the [2+2] Cycloadducts of 3-Triflyloxyarynes” J. Am. Chem. Soc. 2017, 139, 623-626. (Most read 20 articles on JACS in Feb. 2017)

[2] Yuanyuan Li; Dachuan Qiu; Rongrong Gu; Junli Wang; Jiarong Shi; Yang Li* “Aryne 1,2,3-Trifunctionalization with Aryl Allyl Sulfoxides” J. Am. Chem. Soc. 2016, 138, 10814-10817. (Highlighted by JACS Spotlights: “One-shot Hat Trick on Arynes” 2016, 138, 12003-12004.)

[1] Jiarong Shi; Dachuan Qiu; Juan Wang; Hai Xu; Yang Li* “Domino Aryne Precursor: Efficient Construction of 2,4-Disubstituted Benzothiazoles” J. Am. Chem. Soc. 2015, 137, 5670-5673. (Highlighted by Synfacts 2015, 11, 0701; Invited highlight article by SYNPACTS, 2015)