Baosheng Li, Professor

Email: libs@cqu.edu.cn, libaoshengqq@163.com, Homepage: Li Lab.

Address: Room LC 711, School of Chemistry and Chemical Engineering, Chongqing University.

Mobil Phone: 86-15826063819.

Prof. Li obtained his BS degree in Pharmaceutical Engineering from Guizhou University in 2008. And he received his Ph.D degree in Organic Synthesis from Lanzhou University in 2013. From 2012 to 2013, he was a research assistant in The Chinese University of Hong Kong. From 2013 to 2016, he was a postdoctoral fellow in the Nanyang Technological University. Since 2016, he has been a professor of organic chemistry at Chongqing University. Prof. Li’s research interests focus on Organic Synthetic Chemistry and Chemobiology.

Research Direction:
Heterocycles chemistry，Pericyclic reaction and Transition-metal catalysis.

Selected Paper:

Xin X,^‡ Liu Y,^‡ Zhou L, Li Y, Luo H, Liu L, Bai R, Lan Y*, Li B*. Regiospecific constructing m-alkenyl benzaldehyde from β-bromoenal and vinyl borate. Chemical Communications, 2022, in press, DOI: 10.1039/D2CC01441F.

Luo H, Lu Q, Xu M, Gu M, Li B*. Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols. Synthesis, 2022, in press, DOI: 10.1055/a-1790-2282.

Luo H,^‡ Li Y,^‡ Zhang Y, Lu Q, An Q, Xu M, Li S, Li J, Li B*. Nucleophilic Aromatic Substitution of 5-Bromo-1,2,3-triazines with Phenols. The Journal of Organic Chemistry, 2022, 87(5): 2590-2600.

Xu M, ^‡ Liu L, Wang T, Luo H, Hou M, Du L, Xin X, Lu Q, Li B*. Acid-catalyzed ring-expansion of 4-(1-hydroxycyclobutyl)-1,2,3-triazoles. Organic Chemistry Frontiers, 2022, 9(4), 1065-1069.

Du L,^‡ Gong Y,^‡ Han J, Xin X, Luo H, Tian Y, Li Y, Li B*. Cascade 8π Electrocyclization/Benzannulation to Access Highly Substituted Phenylpyridines. Organic Letters, 2021, 23(20): 7966-7971.

Luo H,^‡ Li Y,^‡ Du L, Xin X, Wang T, Han J, Tian Y, Li B*. Divergent Synthesis of Highly Substituted Pyridines and Benzenes from Dienals, Alkynes, and Sulfonyl Azides. Organic Letters, 2021, 23(20): 7883-7887.

Li Y,^‡ Luo H,^‡ Tang Z, Li Y, Du L, Xin X, Li S, Li B*. Copper and Rhodium Relay Catalysis for Selective Access to cis-2,3-Dihydroazepines. Organic Letters, 2021, 23(16): 6450-6454.

Wang T, ^‡ Tang Z, Luo H, Tian Y, Xu M, Lu Q, Li B*. Access to (Z)-β-Substituted Enamides from N1-H-1,2,3-Triazoles. Organic Letters, 2021, 23(16): 6293-6298.

Li S, ^‡ Li X, Lu Y, Hou M, Xu Z, Li B*. A thiol-responsive and self-immolative podophyllotoxin prodrug for cancer therapy. Tetrahedron Lett. 2021, 71, 153044.

An Q, ^‡ Liu L, Tang Z, Luo H, Li Y, Xu M, Li B*. Access to thiazoles via [3 + 2] cycloaddition of 1,2,3-thiadiazoles with isonitriles. Organic Chemistry Frontiers, 2021, 8(12): 2909-2913.

Zhang Y,^‡ Luo H,^‡ Lu Q, An Q, Li Y, Li S, Tang Z, Li B*. Access to pyridines via cascade nucleophilic addition reaction of 1,2,3-triazines with activated ketones or acetonitriles. Chinese Chemical Letters, 2021, 32(1): 393-396.

Zhang Y,^‡ Luo H,^‡ Lu Q, An Q, Li Y, Li S, Tang Z, Li B*. Access to pyridines via cascade nucleophilic addition reaction of 1,2,3-triazines with activated ketones or acetonitriles. Chinese Chemical Letters, 2021, 32(1): 393-396.

Hou M,^‡ Li S, Xu Z*, Li B*. A Reduction-responsive Amphiphilic MethotrexatePodophy -llotoxin Conjugate for Targeted Chemotherapy. Chem.–Asian J., 2019, 14, 3840–3844.

Li B,^‡ Wang Y, Rupert S. J. Proctor, Jin Z, Yonggui Robin Chi*. Carbene-catalyzed desymmetrization of 1,3-diols: access to optically enriched tertiary alkyl chlorides. Chem Commun, 2016, 52, 8313.

Li B,^‡ Wang Y, Rupert S. J. Proctor, Zhang Y, Richard D. Webster, Yang S, Song B, Yonggui Robin Chi*. Carbene-catalyzed reductive coupling of nitrobenzyl bromides and ketones via single-electron-transfer process. Nature Communications, 2016, 7, 12933.

Huang Z, Huang X, Li B, Mou C, Yang S, Song B, Yonggui Robin Chi*. Access to P-Stereogenic Phosphinates via N-Heterocyclic Carbene-Catalyzed Desymmetriza-

tion of Bisphenols. J. Am. Chem. Soc. 2016, 138, 7524.

Li B,^‡ Wang Y, Jin Z, Yonggui Robin Chi*. Cycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts. Chemical Science, 2015, 6, 6008.

Li B,^‡ Wang Y, Jin Z, Zheng P, Rakesh Ganguly & Yonggui Robin Chi*. Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone. Nature Communications, 2015, 6, 6207.

Zhu T, Mou C, Li B, Marie Smetankova, Song B, Yonggui Robin Chi*. N-Heterocyclic Carbene-Catalyzed δ-Carbon LUMO Activation of Unsaturated Aldehydes. J. Am. Chem. Soc. 2015, 137, 5658.

Wang S, Li B, Tu Y*. Catalytic asymmetric semipinacol rearrangements. Chem. Commun., 2014, 50, 2393.

Wang L, Shi Z, Cao X*. Li B, An P. Construction of fused- and spiro-oxa-[n.2.1] skeletons by a tandem epoxide rearrangement/intramolecular [3+2] cycloaddition of cyclopropanes with carbonyls. Chem. Commun., 2014, 50, 8061.

Li B,^‡ Liu W, Zhang F, Wang S, Tu Y*, Cao X*. Direct Synthesis of Spiro- and Fused-Hydrofurans via Tunable Tandem Semipinacol Rearrangement/Oxa-Michael Addition. Chemistry - A European Journal, 2013, 19,5246.

Zhang Y, Zhang X, Li B, Xiang K, Zhang F, Wang S, Tu Y*. Catalytic intermolecular carbon electrophile induced semipinacol rearrangement. Chem. Commun., 2013, 49,1648.

Li B,^‡ Yang B, Wang S, Zhang Y, Cao X*, Tu Y*. Copper(I)-catalyzed Intramolecular   [2 + 2] Cycloaddition of 1,6-enyne-derived Ketenimine: an Efficient Construction of Strained and Bridged 7-substituted-3-Heterobicyclo[3.1.1]heptan-6-one. Chemical Science, 2012, 3, 1975.

Zhang Y, Zhu D, Li B, Tu Y*. Lu Y. Wang S. Palladium-Catalyzed Cascade Process To Construct 1,2,5-Trisubstituted Pyrroles. J. Org. Chem., 2012, 77, 4167.

Li B,^‡ Zhang E, Zhang Q, Zhang F, Tu Y*, Cao X*. One-Pot Construction of Multi-

Substituted Spiro-Cycloalkanediones by an Organocatalytic Asymmetric Epoxidati-

on/Semipinacol Rearrangement. Chem-Asian. J, 2011, 6, 2269.

Zhang Y, Zhu D, Jiao Z, Li B, Zhang F, Tu Y*. Regiodivergent Annulation of AlkynylIndoles To Construct Spiro-pseudoindoxyl and Tetrahydro-β-carbolines. Org. Lett, 2011, 13, 3458.

Zhang J, Qi X, Chen J, Li B, Zhou Y, Cao X*. Total Synthesis of Malyngamides K, L, and 5′′-epi-C and Absolute Configuration of Malyngamide L. J. Org. Chem., 2011, 76, 3946.