张起辉-重庆大学化学化工学院

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张起辉，教授/博士生导师。2010年毕业于药学专业学府“沈阳药科大学”，师从著名天然药物学家裴月湖教授和吴立军教授；曾在世界十大名校之一的美国芝加哥大学进行访学，师从国际著名药学家Yuan Cunsu教授。2010年至今，就职于重庆大学。

作为项目负责人主持和主研国家级项目5项，主持和主研省部级项目7项，主持和主研企业横向课题多项，发表SCI论文数十篇，获专利十余项。

曾获重庆市青年教师讲课比赛二等奖；重庆大学青年教师讲课比赛一等奖；重庆大学化学化工学院讲课比赛一等奖；重庆大学总工会表彰；重庆大学最受学生欢迎十佳教师；重庆大学教学工作优秀教师；重庆大学优秀青年教师；重庆大学先进工作者；唐立新奖教金获得者；爱以森优秀教师奖教金获得者。

联系方式

E-mail：qhzhang@cqu.edu.cn Tel：15123116558

研究方向

应用新材料开拓中药研究新方法：基于分子印迹材料和各种新材料，以及固相萃取及微萃取等新技术，开拓中药组分研究新方法，拓展中药研究新领域。

天然产物提取分离与结构修饰：基于重庆道地药材，研究其中主要的化学成分，建立新颖的筛选体系，在类型繁多的化合物中找到具有开发前景的化合物，根据构效关系进一步进行结构修饰，希望使其发挥更大的药效。

天然产物的应用研究：在找到具有开发前景的化学物质的基础上，进一步根据化合物的理化性质和治疗方向确定工艺和剂型，为药物的临床开发或保健品开发奠定物质基础。

代表性论文、专著和专利

近年代表作：

1) Zhang Qi-Hui*, Zhou Lian-Di, Chen Hua, Wang Chong-Zhi, Xia Zhi-Ning*, Yuan Chun-Su. Solid-phase microextraction technology for in vitro and in vivo metabolite analysis. TRAC-TREND ANAL CHEM, 2016, 80: 57-65. (IF=13.1, Q1)

2) Jia-Yuan He, Qin Li, Hui-Xian Xu, Qin-Yue Zheng, Qi-Hui Zhang*, Lian-Di Zhou, Chong-Zhi Wang, Chun-Su Yuan. Recognition and analysis of biomarkers in tumor microenvironments based on promising molecular imprinting strategies with high selectivity. TRAC-TREND ANAL CHEM, 2023, 162: 117033. (IF=13.1, Q1)

3) Hu-Xian Xu, Yan-Jun Li, Qin Li, Dan-Dan Yang, Ting Li, Sai-Meng Jin, Lian-Di Zhou, Qi-Hui Zhang*, James H. Clark. Reactive oxygen species induced by plant essential oil for effective degradation of p-phenylenediamine. GREEN CHEM, 2023, 25(14): 5647-5653. (IF=11.0, Q1)

4) Yan-Jun Li, Li-Li Yang, Li Ni, Jia-Min Xiong, Jia-Yuan He, Lian-Di Zhou, Ling Luo, Qi-Hui Zhang*, Chun-Su Yuan. Constructing electrochemical sensor using molecular-imprinted polysaccharide for rapid identification and determination of l-tryptophan in diet. FOOD CHEM, 2023, 425: 136486. (IF=8.8, Q1)

5) Shu-Xian Wang, Rong-Rong Ma, Ying Z. Mazzu, Jia-Wei Zhang, Wei Li, Ling Tan, Lian-Di Zhou*, Zhi-Ning Xia, Qi-Hui Zhang*, Chun-Su Yuan. Specific adsorption of tetracycline from milk by using biocompatible magnetic molecular imprinting material and evaluation by ECD. FOOD CHEM, 2020, 326: 126969. (IF=8.8, Q1)

6) Jia-Yuan He, Qing-Yao Li, Li-Li Yang, Rong-Rong M, Chong-Zhi Wang, Lian-Di Zhou, Qi-Hui Zhang*, Zhi-Ning Xia, Chun-Su Yuan. Synergistic recognition of transferrin by using performance dual epitope imprinted polymers. ANAL CHIM ACTA, 2021, 1186: 339117. (IF=6.2, Q1)

7) Jia-Wei Zhang, Jia-Yuan He, Chong-Zhi Wang, Feng-Qing Yang, Lian-Di Zhou, Qi-Hui Zhang*, Zhi-Ning Xia, Chun-Su Yuan. Simultaneous extraction of several targets by using non-toxic dual template molecularly imprinted polymers in vivo and in vitro. Talanta, 2020, 219: 121283. (IF=6.1, Q1)

8) Jia-Wei Zhang, Ling Tan, Jin-Bin Yuan, Ri-Fa Qiao, Chong-Zhi Wang, Feng-Qing Yang, Lian-Di Zhou, Qi-Hui Zhang*, Zhi-Ning Xia, Chun-Su Yuan. Extraction of activated epimedium glycosides in vivo and in vitro by using bifunctional-monomer chitosan magnetic molecularly imprinted polymers and identification by UPLC-Q-TOF-MS. Talanta, 2020, 219, 121350. (IF=6.1, Q1)

9) Zong-Liang Sun, Yu-Zhen Zhang, Zhang Feng, Jia-Wei Zhang, Guo-Can Zheng, Ling Tan, Chong-Zhi Wang, Lian-Di Zhou, Qi-Hui Zhang*, Chun-Su Yuan. Quality assessment of Penthorum chinense Pursh through multicomponent qualification and fingerprint, chemometric, and antihepatocarcinoma analyses. FOOD FUNCT, 2018, 9 (7): 3807-3814. (IF=6.1, Q1)

10) Yu-Zhen Zhang, Jia-Wei Zhang, Chong-Zhi Wang, Lian-Di Zhou, Qi-Hui Zhang*. Polydopamine-Coated Magnetic Molecularly Imprinted Polymers with Fragment Template for Identification of Pulsatilla Saponin Metabolites in Rat Feces with UPLC-Q-TOF-MS. J AGR FOOD CHEM, 2018, 66: 653-660. (IF=6.1, Q1)

11) Die Gao, Dan-Dan Wang, Qian Zhang, Feng-Qing Yang, Zhi-Ning Xia*, Qi-Hui Zhang *, Chun-Su Yuan. In Vivo Selective Capture and Rapid Identification of Luteolin and Its Metabolites in Rat Livers by Molecularly Imprinted Solid-Phase Microextraction. J AGR FOOD CHEM, 2017, 65(6): 1158-1166. (IF=6.1, Q1)

12) Jia-Yuan He, Hui-Xian Xu, Qin Li, Qin-Yue Zheng, Qin-Yue Zheng, Lian-Di Zhou, Ling Luo, Qi-Hui Zhang*, Chun-Su Yuan. Specific capture and determination of glycoprotein using a hybrid epitopes and monomers-mediated molecular-imprinted polymer enzyme-free electrochemical biosensor. MICROCHIM ACTA, 2023, 190: 118. (IF=5.7, Q1)

专利：

1) 一种用于圈党种植的装置, 2018.6.14, 中国, 201810611765.7；

2) 一种从牛蒡子中分离牛蒡子油、牛蒡苷、牛蒡苷元、牛蒡酚E和牛蒡酚H的方法, 2016.11, 中国, 201610129419.6；

3) 利用蛇足石杉细胞和内生真菌共培养富集石杉碱甲的方法, 2015.6, 中国, 201510325447.0;

4) 一种治疗烧烫伤的新型大黄素明胶微球与纳米银复合凝胶制剂, 2015.6, 中国, 201510368421.4;

5) 多功能塑料布, 2014.7, 中国, 201420373633.2;

6) 干伞器, 2014.7, 中国, 201420373609.9;

7) 一种柠檬苦素苷的提取分离技术与生产工艺, 2013.12, 中国, 201310694615.4;

8) 一种可添加在旋转蒸发仪冷凝器外的节能保护罩, 2013.12, 中国, 201320817162.5;

9) 一种治疗前列腺炎的栓剂及其制备方法, 2012.6, 中国, 201210191464.6;

10) 聚酮类化合物及其应用, 2010.6, 中国, 201010572308.5;

11) 新的呋喃类衍生物及其应用, 2010.8, 中国, 201010174476.9;

12) 新的薁类化合物及其应用, 2009.12, 中国, 200910012313.8。