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李沙瑜,教授。1977年生,重庆人,1999年获南开大学化学学士学位,2005年获中国科学院化学研究所有机化学博士学位。2005-2016年期间,中国科学院化学研究所任助理研究员、副研究员。



主持国家自然科学基金项目4项、中央高校科研项目1项,参加科技部973项目1项、国家自然科学基金重大研究计划重点支持项目1项。作为第一作者或通讯作者发表SCI论文20篇,累计他引超过600次,其中1篇被ISI Web of Knowledge选为ESI高引用论文,被国际著名化学评论期刊“Synfacts”作为研究亮点介绍。获授权发明专利4项(排名前三)。获得中国分析测试协会科学技术奖二等奖(CAIA奖)(第三获奖人)。

 

联系方式

重庆大学虎溪校区理科楼LC427 Emailshakl@163.com

研究方向


有机发光材料的设计及性质研究:本方向基于对材料光物理性质的理解,技术上依托量化计算预测、有机合成制备和光学性质测试,以构筑高性能发光体系为科学目标。


发光探针研究:本方向通过对高性能发光材料的功能化,实现对环境参量、污染物及生物活性物种的原位发光检测。

代表性论文、专著和专利

1. Liu, J.; Guo, X. D.; Hu, R.; Liu, X. Y.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability Analytical Chemistry, 2016, 88, 1052..


2. Cao, L. X.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* In vivo observation of the pH alternation in mitochondria upon various external stimuli Chemical Communications, 2015, 51, 17324


3. Liu, J.; Guo, X. D.; Hu, R.; Xu, J.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Intracellular Fluorescent Temperature Probe Based on Triarylboron Substituted Poly N-Isopropylacrylamide and Energy Transfer Analytical Chemistry, 2015, 87, 3694.


4. Cao, L. X.; Li, X. Y.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* A novel nanogel-based fluorescent probe for ratiometric detection of intracellular pH values Chemical Communications2014, 50, 8787.


5. Li, X. Y.; Guo, X. D.; Cao, L. X.; Xun, Z. Q.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Water-Soluble Triarylboron Compound for ATP Imaging In Vivo Based on Analyte Induced Aggregation Angewandte Chemie-International Edition2014, 53, 7809.


6. Feng, J.; Xiong, L.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Fluorescent Temperature Sensing Using Triarylboron Compounds and Microcapsules for Detection of a Wide Temperature Range on the Micro- and Macroscale Advanced Functional Materials 2013, 23, 340.


7. Xiong, L.; Feng, J.; Hu, R.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Sensing in 15 s for Aqueous Fluoride Anion by Water-Insoluble Fluorescent Probe Incorporating Hydrogel Analytical Chemistry 2013, 85, 4113.


8. Yang, G. Q.*; Zhang, K.; Gong, F. B.; Liu, M.; Yang, Z. P.; Ma, J. S.; Li, S. Y.* Large nanoparticle-induced enhancement of recognition selectivity for Cu2+ ion Sensors and Actuators B-Chemical 2011, 155, 848.


9. Tian, K. J.; Hu, D. H.; Hu, R.; Wang, S. Q.; Li, S. Y.*; Li, Y.*; Yang, G. Q.* Multiple fluorescence Delta CIE and Delta RGB codes for sensing volatile organic compounds with a wide range of responses Chemical Communications 2011, 47, 10052.


10.Hu, R.; Li, S. Y.*; Zeng, Y.; Chen, J. P.; Wang, S. Q.; Li, Y.*; Yang, G. Q.* Understanding the aggregation induced emission enhancement for a compound with excited state intramolecular proton transfer character Physical Chemistry Chemical Physics 2011, 13, 2044.


11.Feng, J.; Tian, K. J.; Hu, D. H.; Wang, S. Q.; Li, S. Y.*; Zeng, Y.; Li, Y.*; Yang, G. Q.* A Triarylboron-Based Fluorescent Thermometer: Sensitive Over a Wide Temperature Range Angewandte Chemie-International Edition 2011, 50, 8072.

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