设为首页  |  加入收藏
 首 页  学院总览  人才培养  科学研究  党群院务  学生工作  招生就业  校友园地  安全工作 
当前位置: 首 页>>学院总览>>师资队伍>>预聘制研究员>>正文
 
李葆生
2017-04-13 10:14   审核人:


            李   特聘研究员、博士生导师

                             出生: 19854

                             电话: 15826063819

                             邮箱: libs@cqu.edu.cnlibaoshengqq@163.com

                             地址: 重庆大学虎溪校区化学化工学院711

 

欢迎对有机合成化学、化学生物学感兴趣的同学加入本课题组的硕士及博士研究生!

          


研究兴趣

1.有机合成方法学的发展

2. 药物分子、活性化合物的合成及生物活性研究

3. 小分子靶向药物的合成及其在肿瘤诊疗和转化医学等领域中的应用

 

教育背景

2008-2013  博士  兰州大学 化学化工学院 有机合成 (导师:涂永强 院士;曹小平 教授)

2004-2008  学士  贵州大学 化学化工学院 制药工程

 

工作经历

2016-至今  特聘研究员  重庆大学 化学化工学院

2013-2016  博后        新加坡南洋理工大学 化生系 (导师: Robin Chi 教授)

2012-2013  研究助理    香港中文大学, 化学院 (导师: Hak-Fun Chow 教授)

 

获人才计划及主持基金项目情况

1.       中国科协青年人才托举项目基金 (所有化学学科2017年共8人入选)

2.       国家自然科学基金面上项目

3.       重庆大学“青年百人计划”基金

          


以第一作者发表论文

7. Carbene-catalyzed reductive coupling of nitrobenzyl bromides and ketones via single-electron-transfer process. Bao-Sheng Li; Yuhuang, Wang; Rupert S. J. Proctor; Yuexia Zhang; Richard D. Webster; Song Yang; Baoan Song; Yonggui Robin Chi*, Nature Communications. 2016, 7, in press.

6. Carbene-catalyzed desymmetrization of 1,3-diols: access to optically enriched tertiary alkyl chlorides. Bao-Sheng Li; Yuhuang, Wang; Rupert S. J. Proctor; Zhichao, Jin; Yonggui Robin Chi*, Chem. Commun, 2016, 52, 8313.

5. Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral    organocatalyst to ketone. Bao-Sheng, Li; Yuhuang Wang, Zhichao Jin, Pengcheng Zheng, Rakesh GangulyYonggui Robin Chi*, Nature Communications. 2015, 6, 6207.

4. Cycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts. Bao-Sheng Li, Yuhuang Wang, Zhichao Jin and Yonggui Robin Chi*, Chemical Science, 2015, 6, 6008.

3. Direct Synthesis of Spiro- and Fused-Hydrofurans via Tunable Tandem Semipinacol Rearrangement/Oxa-Michael Addition. Bao-Sheng, Li; Wen-Xing, Liu; Fu-Min, Zhang; Shao-hua, Wang; Yong-Qiang, Tu*; Xiao-Ping, Cao*, Chenistry - A European Journal, 2013, 19, 5246.

2. Copper(I)-catalyzed Intramolecular [2 + 2] Cycloaddition of 1,6-enyne-derived Ketenimine: an Efficient Construction of Strained and Bridged 7-substituted-3- Heterobicyclo[3.1.1]heptan-6-one. Bao-Sheng Li; Bin-Miao, Yang; Shao-Hua, Wang; Yong-Qiang, Zhang; Xiao-Ping, Cao*; Yong-Qiang, Tu*, Chemical. Science., 2012, 3, 1975.Highlighted by Synfacts, 2012, 8, 0868.

1.       One-Pot Construction of Multi-Substituted Spiro-Cycloalkanediones by an Organocatalytic

Asymmetric Epoxidation/Semipinacol Rearrangement. Bao-Sheng, Li; En, Zhang; Qing-Wei, Zhang; Fu-Min, Zhang; Yong-Qiang, Tu*; Xiao-Ping Cao*, Chem–Asian. J., 2011, 6, 2269.

 

以共同作者发表论文

8. Access to P-Stereogenic Phosphinates via N-Heterocyclic Carbene-Catalyzed Desymmetrization of Bisphenols. Zhijian Huang, Xuan Huang, Baosheng Li, Chengli Mou, Song Yang, Bao-An Song, and Yonggui Robin Chi. J. Am. Chem. Soc.2016138, 7524.

7. N-Heterocyclic Carbene-Catalyzed δ-Carbon LUMO Activation of Unsaturated Aldehydes.. Tingshun Zhu, Chengli Mou, Baosheng Li, Marie Smetankova, Bao-An Song, and Yonggui Robin Chi*, J. Am. Chem. Soc.2015137, 5658.

6. Catalytic asymmetric semipinacol rearrangements. Shao-Hua Wang, Bao-Sheng Li and Yong-Qiang Tu, Chem. Commun., 2014, 50, 2393.

5. Construction of fused- and spiro-oxa-[n.2.1] skeletons by a tandem epoxide rearrangement/intramolecular [3+2] cycloaddition of cyclopropanes with carbonyls. Lu-Feng Wang, Zi-Fa Shi, Xiao-Ping Cao*, Bao-Sheng Li and Peng An. Chem. Commun., 2014, 50, 8061.

4. Catalytic intermolecular carbon electrophile induced semipinacol rearrangement. Qing-Wei Zhang, Xiao-Bo Zhang, Bao-Sheng Li, Kai Xiang, Fu-Min Zhang, Shao-Hua Wang and Yong-Qiang Tu*.  Chem. Commun., 2013, 49, 1648.

3. Palladium-Catalyzed Cascade Process To Construct 1,2,5-Trisubstituted Pyrroles. Yong-Qiang, Zhang; Dao-Yong, Zhu; Bao-Sheng, Li; Yong-Qiang, Tu*; Yong, Lu; Sho-Hua, Wang. J. Org. Chem., 2012, 77, 4167.

2. Total Synthesis of Malyngamides K, L, and 5′′-epi-C and Absolute Configuration of         Malyngamide L. Jun-Tao, Zhang; Xian-Liang, Qi; Jie, Chen; Bao-Sheng, Li; You-Bai, Zhou; Xiao-Ping, Cao*. J. Org. Chem., 2011, 76, 3946.

1. Regiodivergent Annulation of AlkynylIndoles To Construct Spiro-pseudoindoxyl and Tetrahydro-β-carbolines. Yong-Qiang, Zhang; Dao-Yong, Zhu; Zhi-Wei, Jiao; Bao-Sheng, Li; Fu-Min, Zhang; Yong-Qiang, Tu*, Org. Lett., 2011, 13, 3458.

 

 

 

 

 

 

关闭窗口
领导信箱 | 校园风光 | 网站地图 | 英文网站
版权所有 高校主站