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夏之宁
2017-04-12 20:51   审核人:

夏之宁 教授/博士生导师,重庆大学校长助理,1995年毕业于丹麦哥本哈根大学,获博士学位。教育部跨世纪优秀人才,教育部高等学校青年教师奖,国务院政府特殊津贴获得者。中国色谱学会理事,重庆市分析化学学科学术带头人,重庆市色谱学会理事长,重庆市分析测试学会副理事长。《色谱》、《环境化学》等杂志编委。

先后主持科技部国际科技合作项目、科技部国家基础研究规划项目(973计划)、国家自然科学基金项目、教育部“高校骨干教师基金”项目以及重庆市重点项目20余项;在SCI收录期刊上发表论文100余篇,出版专著2本,教材3本,获8项专利。

主要研究方向包括以下三个方面。1活性天然产物:创新方法筛选中药中的活性成分;改进及应用现代制备技术从中药中获得活性单体成分;活性成分的分子、细胞及动物水平评价。2药物分析化学:手性分离分析方法研究;药物亲和分析;功能化毛细管电泳分析方法的建立及应用。3微波化学与波谱:微波化学反应的机理、微波热与非热作用、微波在有机化学、分析化学、材料化学中的应用。

联系方式: Emailznxia@cqu.edu.cnTeloffice):023-65678588023-65678669

5年代表性论文:

[1] Q.F. Fu, F.Q. Yang, H. Chen, Z.N. Xia, Enhancement of enantioselectivity in chiral capillary electrophoresis using hydroxypropyl-beta-cyclodextrin as chiral selector under molecular crowding conditions induced by dextran or dextrin. Electrophoresis, 2014, 35(20): 2938-2945.

[2] F. Li, R. Liu, F.Q. Yang, W. Xiao, C. Chen, Z.N. Xia, Determination of three curcuminoids in Curcuma longa by microemulsion electrokinetic chromatography with protective effects on the analytes, Analytical Methods, 2014, 6(8): 2566-2571.

[3] Q. Gou, L.B. Favero, S.S. Bahamyirou, Z.N. Xia, W. Caminati, Interactions between Carboxylic Acids and Aldehydes: A Rotational Study of HCOOH-CH2O. Journal of Physical Chemistry A, 2014, 118(45): 10738-10741.

[4] G. Feng, Q. Gou, L. Evangelisti, Z.N. Xia, W. Caminati, Conformational equilibria in carboxylic acid bimolecules: a rotational study of acrylic acid-formic acid. Physical Chemistry Chemical Physics, 2013, 15(8): 2917-2922.

[5] F.Q. Yang, J. Yang, X.M. Zhang, P. Xu, Z.N. Xia, Analysis of volatile components in Curcuma rhizome by microemulsion electrokinetic chromatography, Journal of Chromatographic Science, 2013, 51(2): 155-160.

[6] J. Du, Z.N. Xia, Measurement of the catalytic activity of gold nanoparticles synthesized by a microwave-assisted heating method through time-dependent UV spectra, Analytical Methods, 2013, 5(8): 1991-1995.

[7] F. Li, F.Q. Yang, Z.N. Xia, Simultaneous Determination of Ten Nucleosides and Related Compounds by MEEKC with [BMIM]PF6 as Oil Phase, Chromatographia, 2013, 76 (15-16): 1003-1011.

[8] Z.N. Xia, Y.X. Lin, L.X. Guo, F.Q. Yang, P. Xu, Y.L. Zhang, J.H. Liu, Development of a cell-based high-throughput peroxisome proliferator-activated receptors (PPARs) screening model and its application for evaluation of the extracts from Rhizoma Coptis, Journal of Asian Natural Products Research, 2013, 15(3): 225-234.

[9] Z.H. Li, G. Chen, S. Qiao, R.H. Liang, C. Lan, Z.N. Xia, Design and Synthesis of Some New N-Phenylanthranilic Acids from Highly Sterically Hindered Anilines, Synthetic Communications, 2013, 43 (9): 10.

[10] H.L. Zuo, F.Q. Yang, W.H. Huang, Z.N. Xia, Preparative gas chromatography and its applications, Journal of Chromatographic Science, 2013, 51(7): 704-715.

[11] H.L. Zuo, S.J. Chen, D.L. Zhang, J. Zhao, F.Q. Yang, Z.N. Xia, Quality evaluation of natural Cordyceps sinensis from different collecting places in China by the contents of nucleosides and heavy metals, Analytical Methods, 2013, 5(20): 5450-5456.

[12] C. Chen, F.Q. Yang, H.L. Zuo, Y.L. Song, Z.N. Xia, W. Xiao, Applications of biochromatography in the screening of bioactive natural products, Journal of Chromatographic Science, 2013, 51(8): 780-790.

[13] L.X. Li, Z.N. Xia, F.Q. Yang, H. Chen, Y.L. Zhang, Enantioselective analysis of ofloxacin enantiomers by partial-filling capillary electrophoresis with bacteria as chiral selectors, Journal of Separation Science, 2012, 35(16): 2101-2107.

[14] F.Q. Yang, R. Lv, Y.L. Zhang, and Z.N. Xia, Comparison study on nucleosides and nucleotides in edible mushroom species by capillary zone electrophoresis, Analytical Methods, 2012, 4(2): 546-549.

[15] L.X. Guo, Z.N. Xia, X. Gao, F. Yin, J.H. Liu, Glucagon-like peptide 1 receptor plays a critical role in geniposide-regulated insulin secretion in INS-1 cells, Acta Pharmacologica Sinica, 2012, 33(2): 237-241.

[16] J. Du, Z.N. Xia, Interactions of gold nanoparticles and lysozyme by fluorescence quenching method, Analytical Letters, 2012, 45 (15): 2236-2245.

[17] P. Xu, Z.N. Xia, Y.X. Lin, Chemical constituents from Edgeworthia gardneri (Thymelaeaceae), Biochemical Systematics and Ecology, 2012, 45: 148-150.

[18] Z.T. Chen, Z.B. Zhong, Z.N. Xia, F.Q. Yang, X.J. Mu, Separation of Fluoroquinolones by MEKC Modified with Hydrophobic Ionic Liquid as a Modifier, Chromatographia, 2012, 75 (1-2): 65-70.

[19] Z.H. Li, S.Y. Xiao, R.H. Liang, Z.N. Xia, Synthesis of 2-(arylamino)nicotinic acids in high-temperature water, Research on Chemical Intermediates, 2012, 38(7): 1691-1697.

[20] H.L. Zuo, F.Q. Yang, X.M. Zhang, Z.N. Xia, Separation of cis- and trans-Asarone from Acorus tatarinowii by Preparative Gas Chromatography, Journal of Analytical Methods in Chemistry, 2012, 2012: 402081.

[21] X.J. Mu, N.N. Yu, C.S. Wang, X.B. Zou, Z. Abulimite, Z.N. Xia, Evaluation of a new substrate for measurement of serum PON arylesterase activity, Talanta, 2012, 88 :711-716.

[22] X.M. Jiang, Z.N. Xia, L.H. Deng, W.L. Wei, J. Chen, J.M. Xu, H.Y. Li, Evaluation of Accuracy for the Measurement of Octanol-Water Partition Coefficient by MEEKC, Chromatographia, 2012, 75 (7-8): 347-352.

[23] Y. Wang, F. Li, F.Q. Yang, H.L. Zuo, Z.N. Xia, Simultaneous determination of α-, β- and γ-asarone in Acorustatarinowii by microemulsion electrokinetic chromatography with [BMIM]PF6 as oil phase, Talanta, 2012, 101: 510-515.

[24] G. Feng, L. Evangelisti, L.B. Favero, J.U. Grabow, Z.N. Xia, W. Caminati, On the weak O-H···halogen hydrogen bond: a rotational study of CH3CHClF···H2O. Physical Chemistry Chemical Physics, 2011, 13(31): 14092-14096.

[25] F.Q. Yang, H.K. Wang, H. Chen, J.D. Chen, Z.N. Xia, Fractionation of volatile constituents from curcuma rhizome by preparative gas chromatography, Journal of Automated Methods & Management in Chemistry, 2011, 2011:942467.

[26] J. Yang, Z.N. Xia, F.Q. Yang, R. Lv, Use of Relative Mobility to Estimate Octanol-Water Partition Coefficients of Drugs by Microemulsion Electrokinetic Chromatography, Acta Chimica Sinica, 2011, 69 (7): 810-814.

[27] Z.H. Li, Z.N. Xia, G. Chen, Catalyst-free amination of 2-chloronicotinic acid in water under microwave irradiation, Journal of Chemical Research, 2011, (12): 709-711.

[28] K.Y. Shi, Z.N. Xia, T.T. Gan, X.M. Jiang, C. Xia, Applications of real-time monitoring techniques in chemical synthetic ingredients, Spectroscopy and Spectral Analysis, 2010, 30(2): 499-503.

[29] G.H. Chen, Z.N. Xia, Y. Lu, Prediction of Cell-Penetrating Peptides Using both Support Vector Machine and Linear Discriminant Analysis, Acta Chimica Sinica, 2010, 68(11): 1137-1142.

[30] Z.N. Xia, J. Yang, L.X. Li, F.Q. Yang, X.M. Jiang, Determination of Octanol-Water Partition Coefficients by MEEKC Based on Peak-Shift Assay, Chromatographia, 2010, 72 (5-6): 495-501.

[31] G.H. Chen, Z.N. Xia, Y. Lu, Three-dimensional vector of pharmacophore atomic interaction and its applications to stereoisomeric description, Chemometrics and Intelligent Laboratory Systems, 2010, 102 (2): 91-99.

[32] Y.H. Zhang, Z.N. Xia, L.T. Qin, S.S. Liu, Prediction of blood-brain partitioning: A model based on molecular electronegativity distance vector descriptors, Journal of Molecular Graphics & Modelling, 2010, 29(2): 214-220

[33] Z.N. Xia, T.T. Gan, H. Chen, R. Lv, W.L. Wei, F.Q. Yang, A new open tubular capillary microextraction and sweeping for the analysis of super low concentration of hydrophobic compounds, Journal of Separation Science, 2010, 33(20): 3221-3230.

[34] J.H. Jing, G.Z. Liang, H. Mei, S.Y. Xiao, Z.N. Xia, Quantitative structure-mobility relationship studies of dipeptides in capillary zone electrophoresis using three-dimensional holographic vector of atomic interaction field, Molecular Simulation, 2009, (5): 263-269.

[35] Z.N. Xia, S. Long, S.Y. Xiao, X.B. Zou, A. D'Aurizio, M. Panunzio, Microwave-Assisted Carbonyl-Carbonyl Coupling Route for the Preparation of a Useful Intermediate in the Synthesis of Carbapenems, Synthetic Communications, 2009, 39 (12): 2151-2160.

[36]  L.X. Guo, J.H. Liu, Z.N. Xia, Geniposide inhibits COCl2-induced PC12 cells death via the mitochondrial pathway,Chinese Medical Journal, 2009, 122(23): 2886-2892.

[37] X.M. Jiang, Z.N. Xia, W.L. Wei, Q. Gou, Direct UV detection of underivatized amino acids using capillary electrophoresis with online sweeping enrichment, Journal of Separation Science, 2009, 32 (11): 1927-1933.

[38]  Z.N. Xia, L.X. Li, J. Yang, C.Q. Xiong, Investigation of interaction between the drug and cell membrane by capillary electrophoresis, Science in China Series B-Chemistry, 2009, 52 (12): 2200-2204.


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